Making choices in health: WHO guide to cost-effectiveness analysis

This detailed guide provides investigators with a rigorous technical discussion of the cost-effectiveness analysis (CEA) procedure, written from a public health perspective, as a method for assessing the efficiency of an intervention.

Particular care is taken in the guidance to demonstrate how to maximise the generalisability of results across settings.

Contents

• a brief description of CEA
• overview of CEA study design,
• guidance on cost estimation, discounting, uncertainty, and sensitivity analysis,
• policy uses of CEA, and
• reporting results.

Part II of the guide, in turn, offers several supporting background papers originally published in journals.